2019-04-22, 05:18 PM
New Form of Neural Communication
Peter Dockrill
Peter Dockrill
Quote:Durand and his team investigated slow periodic activity in vitro, studying the brain waves in hippocampal slices extracted from decapitated mice.
What they found was that slow periodic activity can generate electric fields which in turn activate neighbouring cells, constituting a form of neural communication without chemical synaptic transmission or gap junctions.
"We've known about these waves for a long time, but no one knows their exact function and no one believed they could spontaneously propagate," Durand says.
"I've been studying the hippocampus, itself just one small part of the brain, for 40 years and it keeps surprising me."
Quote:The team's most radical finding was that these electrical fields can activate neurons through a complete gap in severed brain tissue, when the two pieces remain in close physical proximity.
"To ensure that the slice was completely cut, the two pieces of tissue were separated and then rejoined while a clear gap was observed under the surgical microscope," the authors explain in their paper.
"The slow hippocampal periodic activity could indeed generate an event on the other side of a complete cut through the whole slice."
If you think that sounds freaky, you're not the only one. The review committee at The Journal of Physiology – in which the research has been published – insisted the experiments be completed again before agreeing to print the study.